Ajit Gopalakrishnan

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Low-power signal-conditioning circuitry for an Intraocular Pressure Sensor in AMI 0.5μm process

This chip was taped out as part of the research project for the advanced graduate level course ECE 703 - Integrated Bio-electronic Circuits. The collaborators on this project were Pradeep Silva and Srinivas Jasti. In this project, our goal was to design a CMOS signal conditioning circuit for an intraocular pressure sensor that allows wireless communication with an external data-logging system. Ours was adjudged the best presentation amongst seven designs

Motivation

The inpsiration for this chip design comes from the need to develop an improved implantable solution for a disease known as Glaucoma. It is the second leading causes of blindness without precursory warnings and the first leading cause of preventable blindness. More than three million Americans suffer from glaucoma, but only half that number are aware that they have it. Blindness arising from glaucoma accounts for 9% to 12% of all cases of blindness in the U.S.

Recent advances in technology and medicine have increased the demand for implantable bioelectronic systems in health care. Add to this the ability of wireless techniques to measure and control various physiological parameters within the body, and we have a bio-electronic system that is an essential tool for the physician in diagnosis and treatment of diseases that afflict the body. Glaucoma is a disease that could benefit from such a system.

Relevant Files

Here is a pdf file of our presentation. More materials will be added soon.

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